The midfielder did not play in his country’s opening 1-1 draw with Wales on Monday, a game that saw Gareth Bale score a late crucial penalty after Timothy Weah’s opener.
Reyna is one of the USA’s leading lights, operating at a high level with Borussia Dortmund and one of the most high-profile players in Gregg Berhalter’s young side.
While the Dortmund youngster was on the bench, Berhalter opted to turn to Brenden Aaronson and Jordan Morris in the second-half, a period in which Wales moved into the ascendancy after largely playing second fiddle for the opening 45 minutes.
The USMNT coach confirmed the 20-year-old was experiencing some “tightness” in his muscle and revealed Morris was introduced in the second-half for his “speed and power”.
After the game, however, Reyna told reporters “I’m 100 percent and I’m good to go.”