Once billed as tournament favourites, the Group B runners-up squeezed into the quarters after losing to Germany before a late victory over Denmark set up a meeting with the hosts.
Spain have so far proved a strong side in possession but lack a cutting edge and have vulnerabilities on the counter that England will be confident of taking advantage of.
Here are all the details ahead of the game...
Date, kick-off time and venue
England vs Spain is scheduled for an 8pm BST kick-off later today (Wednesday, July 20, 2022).
The Amex Stadium in Brighton will host the match.
Where to watch England vs Spain
TV channel: In the UK, the match will be televised live on BBC One, with coverage beginning at 7.30pm
Live stream: The BBC will stream the match for free via their Sport website and iPlayer service.
Live blog: You can follow all the action via Standard Sport’s live blog.
In Pictures | Women’s Euro 2022 (Group A) : Northern Ireland v England
England vs Spain team news
England XI: Earps, Bronze, Bright, Williamson, Daly, Stanway, Walsh, Kirby, Mead, White, Hemp
Spain XI: Batlle, Paredes, Leon, Carmona; Guijarro, Teresa, Bonmati; Cardona, Esther, Mariona
England vs Spain prediction
Spain are shorn of the world’s best female player and struggled to assert their authority in the groups, with England primed to punish them on the counter.
A 3-0 England win.
Head to head (h2h) history and results
England wins: 4
Spain wins: 2