Manchester City must overcome Real Madrid if they are to keep their Champions League hopes alive after the pair were drawn together for a blockbuster playoff tie.

In a fiendish consequence of City’s scratchy league phase, which saw them narrowly avoid early elimination by finishing 22nd, they will face the La Liga leaders and reigning European champions next month. Celtic have been dealt an equally tough assignment in the form of Bayern Munich. The playoff winners will all enter the round of 16 but there is no further safety net for those defeated.

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It means a swift renewal of acquaintances for City and Real, who have contested 10 Champions League ties in the last decade and most recently met in last season’s quarter-finals. City, who were the holders, lost a penalty shootout at the Etihad Stadium after a 4-4 aggregate draw.

City will hope that an uptick in their previously disastrous domestic form helps them go one better and they may be boosted by the fact that their recent signings Omar Marmoush, Abdukodir Khusanov and Vitor Reis can be registered for the knockout stages of the competition. City will host the first leg on 11 February before travelling to the Bernabéu on 19 February.

Celtic’s first post-Christmas Champions League knockout match since 2012-13 will be the first leg against Bayern at Celtic Park on 12 February. Brendan Rodgers’ side go to Germany on 18 February. The teams have not met since two fixtures during the group stage in 2017-18.

Brest v Paris Saint-Germain

Club Brugge v Atalanta

Manchester City v Real Madrid

Juventus v PSV Eindhoven

Monaco v Benfica

Sporting v Borussia Dortmund

Celtic v Bayern Munich

Feyenoord v Milan

Celtic fans face being banned from attending the game in Munich after the club were hit with a Uefa disciplinary notice on Friday. The Scottish champions were on a suspended ban for away fans following a series of fines over the use of pyrotechnics and an incident during the 4-2 defeat at Villa Park on Wednesday has sparked a potential triggering of the punishment. Photographs show someone among the travelling support holding a green smoke canister, which was then thrown on to the pitch

The winners of each tie will play one of Atlético Madrid and Bayer Leverkusen, who have already progressed to the round of 16 after finishing in the top eight of the league phase. Other floundering giants will feel confident of progress. Paris Saint-Germain, who joined City in edging through the league phase on Wednesday’s sprawling final match-day, face an all-French tie against surprise package Brest. In two ties pitching Serie A against the Eredivisie, Juventus play PSV Eindhoven while Milan meet Feyenoord.

Monaco will play Benfica while Sporting come up against a struggling Borussia Dortmund. A tie between Atalanta and Club Brugge completes the playoff pairings.

The playoff draw did not change the picture for Liverpool, Arsenal or Aston Villa, who are already through to the round of 16 in March and knew which four sides they could play. Liverpool face the winners of Brest v PSG or Monaco v Benfica, while Arsenal play the winners of Juventus v PSV or Feyenoord v Milan. Villa will come up against whoever prevails in either Sporting v Dortmund or Club Brugge v Atalanta.

Manchester United and Tottenham both escaped extra Europa League assignments after securing safe passage to the round of 16 with their respective victories on Thursday. They will both face either the winner of the playoff between AZ Alkmaar and Galatasaray, or the victor between Midtjylland and Real Sociedad. Rangers will meet the winners of either FC Twente v Bodø/Glimt or Fenerbahce v Anderlecht

Other Europa League playoffs that catch the eye include Porto’s meeting with Roma and a Dutch-Belgian clash between Ajax and Union Saint-Gilloise.