The Brazilian international only arrived at the club from Lyon on Monday in a deal that could eventually be worth £51.2million.
“He’s not trained with us yet, we’ve only got the paperwork done last night and we’re waiting on him arriving as he’s had to get his visa today,” West Ham boss David Moyes said earlier in the week.
“But look, he’s signed and that’s the important thing. He will be a big player for us.”
The Hammers are without Ben Johnson, who was forced off early in Sunday’s win over Aston Villa, against Spurs, but Aaron Cresswell is available and starts. Moyes returns to a back four, having made the shift from a back three at half-time at Villa Park.
Gianluca Scamacca made his first Premier League start in that match but is not involved tonight, with Michail Antonio starting instead.
“Like anything else, when you play on a Sunday and have a midweek game it can take a bit out of you, so like everyone else we’re recovering,” Moyes added. “It tests your squad and the players you have but hopefully we’ll be okay.”
West Ham XI: Fabianski, Coufal, Kehrer, Zouma, Cresswell, Soucek, Rice, Fornals, Benrahma, Bowen, Antonio.
Subs: Areola, Randolph, Ogbonna, Coventry, Emerson, Downes, Lanzini, Paqueta, Cornet