Spanish giants Barcelona slipped into the Europa League after they were knocked out of the Champions League group stage for the first time in 20 years, and will face a Napoli side who knocked Leicester out and are currently four points off the top of Serie A.
Rangers, meanwhile, finished second behind Lyon in their Europa League group and will welcome the likes of Erling Haaland and Jude Bellingham to Ibrox as they host Dortmund, who are currently second in the Bundesliga.
The knockout playoff round is a new addition to this year’s Europa League, with the group winners - including West Ham - advancing straight to the last-16, while the runners-up and teams dropping out of the Champions League after finishing third in their groups play for the right to join them.
Europa League knockout playoff draw in full
Sevilla vs Dinamo Zagreb
Atalanta vs Olympiacos
RB Leipzig vs Real Sociedad
Barcelona vs Napoli
Zenit St. Petersburg vs Real Betis
Borussia Dortmund vs Rangers
Sheriff vs Braga
Porto vs Lazio