After that they take on Tottenham and Liverpool in the Premier League too, before taking on Manchester City in the FA Cup semi-finals a week on Saturday.
Head coach Mikel Arteta, as a result, will need to manage his squad through those games as Arsenal will have already played seven matches in 21 days after Tuesday’s clash with Leicester.
Arsenal made two changesas they looked to add to their three-match Premier League winning streak. Alexandre Lacazette came in for Eddie Nketiah in attack while Hector Bellerin was preferred to Cedric Soares.
Leicester made one enforced alteration from their weekend victory over Crystal Palace as Ryan Bennett replaced the injured Ben Chilwell in the Foxes defence.
Confirmed team news
Arsenal: Martinez, Mustafi, Luiz, Kolasinac, Bellerin, Ceballos, Xhaka, Tierney, Saka, Lacazette, Aubameyang
Subs: Papastathopoulos, Torreira, Maitland-Niles, Holding, Pepe, Nelson, Willock, Nketiah, Macey
Leicester: Schmeichel, Bennett, Evans, Soyuncu, Justin, Ndidi, Tielemans, Albrighton, Perez, Iheanacho, Vardy
Subs: Morgan, Gray, Ward, Barnes, Choudhury, James, Mendy, Praet, Fuchs