After 20 years without the trophy the Selecao are most synonymous with, there is a confidence within Brazil that Tite’s squad can end their unusually long drought.
Unlike in 2018, there is a supporting cast able to take at least some of the load off Neymar, while their run to the 2021 Copa America final proved their tournament pedigree.
While Brazil are favourites to win Group G, second place looks open. Serbia boast a fearsome attacking line and are being tipped as dark horses, with Switzerland and Cameroon also to contend with.
Here’s everything you need to know about Brazil’s opener...
Date, kick-off time and venue
The World Cup group stage game is scheduled for a 7pm GMT kick-off time on Thursday November 24, 2022.
The Lusail Iconic Stadium in Lusail will host.
Where to watch Brazil vs Serbia
TV channel: The game will be broadcast live free-to-air on BBC One, with coverage starting at 6.30pm.
Live stream: The BBC iPlayer will offer a free live stream, as will the BBC Sport website.
LIVE coverage: Follow all the action LIVE with Standard Sport’s dedicated match blog.
Brazil vs Serbia team news
Brazil XI: Alisson; Danilo, Marquinhos, Thiago Silva, Sandro; Casemiro, Paqueta; Raphinha, Neymar, Vinicius; Richarlison.
Serbia XI: Milinkovic-Savic, Veljkovic, Milenkovic, Pavlovic, Zivkovic, Lukic, Gudelj, Milinkovic-Savic, Mladenovic, Tadic, Mitrovic.
Brazil vs Serbia prediction
Brazil have been so good at grinding out results of late, it would be foolish to bet against them, although Serbia have more than enough quality to hurt teams.
Brazil to win 2-1.
Head to head (h2h) history and results
Brazil wins: 2
Serbia wins: 0
Brazil vs Serbia latest odds
Brazil to win: 2/5
Serbia to win: 13/2
Odds via Betfair (subject to change).