The forward on Wednesday joined from Atletico Madrid on loan for the remainder of the season, and has trained with his new team-mates at Cobham.
With Christian Pulisic out for a “couple of months” and Raheem Sterling no closer to returning, the out-of-form summer addition should partner Kai Havertz in attack.
Ruben Loftus-Cheek is in training but still not fit enough to play after his ankle injury, while Ben Chilwell is slowly edging closer to a return from his hamstring issue.
Chelsea also remain without N’Golo Kante, Edouard Mendy, Reece James, Wesley Fofana and Armando Broja with a total of 10 players out of their west London derby match.
James is back out running on grass and Kante is doing individual training but they are not expected back this week with no precise timeframe given for their respective recoveries.
However, Aubameyang returned from a back injury that kept him out of the 4-0 FA Cup third-round defeat to Manchester City on Sunday.
The Blues pick an experienced side this evening after winning just one of their last eight Premier League matches. The Blues are in 10th, 10 points off the top four places to qualify for the Champions League and three points behind their west London rivals in the Premier League table.
Predicted Chelsea XI (4-3-3): Kepa; Azpilicueta, Thiago Silva, Koulibaly, Chalobah; Kovacic, Jorginho, Mount; Hall, Felix, Havertz.