Sinan Guler starred for Efes with 14 points while Sasha Vujacic and Cenk Akyol grabbed 12 apiece and Esteban Batista 10.
Efes now boast a 5-3 record in Group C.
In Group B,
Zagreb took a brief lead late in the third quarter before the Russian side, led by Nenad Krstic, pulled away in the final period to claim victory.
Jamont Gordon topscored for CSKA with a season-high 18 points, while Krstic netted 14 points and nine rebounds.
Panathinaikos stayed within touching distance of CSKA in Group B with a 94-59 win at Zalgiris Kaunas.
The Greek side, whose record reads 6-2, are now guaranteed at least a second-placed finish.
In other results,
Rounding off the night's action,