The pair, widely recognised as the greatest players of their generation - if not all-time - are shown thinking over the match-up in an image taken by iconic American photographer Annie Leibovitz.
As fans of the Paris Saint-Germain and Manchester United stars looked deeper into the picture, naturally there were those hunting for clues to prove that their chosen hero was the true GOAT.
This boiled down to the chessboard itself, with Messi shown to have taken three of Ronaldo’s pieces to two.
While some suggested this indicated the Argentine had one-upped his former Ballon d’Or rival, others pointed out that the value of Ronaldo’s captures was stronger - having grabbed a rook and a pawn compared to a bishop and two pawns.
Victory is a State of Mind. @Cristiano and #LionelMessi captured by @annieleibovitz for @LouisVuitton. In addition to a long tradition of crafting trunks for the world’s most coveted sporting trophies, the Maison celebrates two of the most talented football players today. pic.twitter.com/AU9kPyI2wL
— Louis Vuitton (@LouisVuitton) November 19, 2022
Twitter was also awash with theories as to who might have won the game of chess, had it played out from these positions.
In fact, it appears to have been taken from a 2017 showdown between Magnus Carlsen and Hikaru Nakamura. That match famously ended in a draw.
Any sense of rivalry between Messi and Ronaldo in recent years has calmed, the Portuguese star recently speaking of his admiration of Messi on and off the pitch.
“Amazing player is magic, top… As a person, we share the stage 16 years, imagine, 16 years. We share. So, I have great relationship with him," Ronaldo told TalkTV.
So the Louis Vuitton photoshoot with Messi/Ronaldo features a game between Magnus and Hikaru from 2017. But… why specifically that one? pic.twitter.com/ETRWaawtra
— GothamChess (@GothamChess) November 20, 2022
“I'm not friend of him in terms of, what I mean friend is the guy who was with you in your house, speaking on the phone, no, but it's like a teammate.
"He’s a guy that I really respect the way he always speak about me. Even his wife or my wife, my girlfriend, they always respect and they're from Argentina. My girlfriend is from Argentina. So good.
"What I am going to say about Messi? A great guy who does great things for football.”