Here’s what can happen on Wednesday night:
Reigning European champions Bayern Munich can qualify by beating Red Bull Salzburg.
A draw will be enough for Hansi Flick’s side if Atletico Madrid avoid defeat by Lokomotiv Moscow.
One point separates Borussia Monchengladbach, Shakhtar Donetsk and Real Madrid in one of the most tightly-contested groups.
Inter cannot be eliminated this week but need to gain ground as they welcome Madrid to the San Siro.
Manchester City only need to draw with Olympiacos in Athens on Wednesday night in order to reach the knockout stages after taking maximum points from their opening three games.
Marseille are cast adrift with no points at the bottom of Group C and will be eliminated if they lose to Porto.
Liverpool’s task is simple: beat Atalanta at Anfield and they will qualify with two games to spare.
A draw will be enough for Jurgen Klopp’s side if Ajax fail to defeat Midtjylland, who are playing to keep their hopes of progression alive.