The Red Rose equalled New Zealand's best-ever tally for successive wins against Scotland and can go one better in Dublin this weekend.
Eddie Jones's side also sealed the Six Nations crown with victory over the Scots, but the England head coach will be determined to complete another perfect tournament after last year's clean sweep.
Here’s the full breakdown ahead of Saturday's clash at the Aviva Stadium…
The match kicks off at the Aviva Stadium at 5pm on Saturday, March 18.
TV AND LIVE COVERAGE
ITV will be broadcasting the match live with build-up from 4pm, while BBC Five Live Sports Extra will provide coverage on the radio.
Alternatively, you can follow the match live on Standard Sport’s live blog. Enter your email address in the box below to receive an alert when our coverage starts.
Billy Vunipola and Anthony Watson will start England's attempt at securing back-to-back Grand Slams when they face Ireland in Dublin on Saturday.
Vunipola replaces Nathan Hughes at number eight and Watson is recalled at the expense of Jack Nowell on the right wing in a straight swap between starting XV and bench.
Elliot Daly continues in the number 11 jersey after passing the return to play protocols for suspected concussion sustained in the 61-21 demolition of Scotland last Saturday.
Ireland XV: J Payne (Ulster), K Earls (Munster), G Ringrose, R Henshaw (both Leinster), S Zebo (Munster), J Sexton (Leinster), K Marmion (Connacht), J McGrath (Leinster), R Best (Ulster, capt), T Furlong (Leinster), D Ryan (Munster), I Henderson (Ulster), CJ Stander (Munster), S O'Brien, J Heaslip (both Leinster)
England XV: M Brown (Harlequins); A Watson (Bath), J Joseph (Bath), O Farrell (Saracens), E Daly (Wasps); G Ford (Bath), B Youngs (Leicester); J Marler (Harlequins) D Hartley (Northampton, capt), D Cole (Leicester), J Launchbury (Wasps), C Lawes (Northampton), M Itoje (Saracens), J Haskell (Wasps), B Vunipola (Saracens)
HEAD TO HEAD
BETTING ODDS (provided by 888Sport)
Ireland to win at 7/5
Draw at 18/1
England to win at 3/5
Odds correct as of 2pm March 18. Click here to place a bet