Brendan Rodgers will hope the Foxes can cling on to a place in the top four in order to return to the Champions League, with Manchester United just outside in fifth on goal difference.
Chris Wilder's side are finishing strongly though, with Chelsea soundly beaten last time out to leave them in pole position to claim a Europa League place.
A five-point gap separates Blades to Leicester, though Wolves in sixth, just a point clear, represent a more realistic target, given seventh is not certain to return European qualification.
Here is our prediction for the game at the King Power Stadium.
We may earn commission from some of the links in this article, but we never allow this to influence our content.
When is it and what time is kick-off?
The match will begin at 6pm on Thursday 16 July at the King Power Stadium.
How can I watch it online and on TV?
The match will be broadcast live on Sky One, Sky Sports Premier League, Sky Sports Arena, Sky Sports Ultra HD and Pick, and Sky subscribers can also stream the game on the Sky Go app.
If you’re not a Sky customer, you can grab a NOWTV Day Pass here to watch without a subscription.
What is the team news?
James Maddison (hip) and Ben Chilwell (foot) are doubts, as is Marc Albrighton, who picked up a knock against Bournemouth. Caglar Soyuncu is out through suspension after his red card.
John Fleck (groin) is a doubt, but Chris Wilder is “hopeful”. Chris Basham (head) has been cleared.
Leicester XI: Schmeichel; Justin, Bennett, Evans, Fuchs; Ndidi; Perez, Praet, Tielemans, Barnes; Vardy
Sheffield United XI: Henderson; Basham, Egan, O’Connell; Baldock, Berge, Norwood, Osborn, Stevens; McBurnie, McGoldrick
What are the odds?
Sheffield United: 29/10
Leicester are crumbling as the finish line approaches, but they still have hope, with Brendan Rodgers’ side clinging on to fourth on goal difference. Blades are flying after thrashing Chelsea too, so we see Chris Wilder’s side gaining a result here, and while an away win wouldn’t shock us, we’ll opt for the draw. 1-1.