The O2 Arena will also stage the Olympic basketball tournament in the 2012 Games - and Euroleague president Jordi Bertomeu said he hoped the competition's season-ending Final Four would reach new heights in London.
"I am confident that the Final Four, which is already an unforgettable experience for Euroleague fans, will take another step forward in London," Bertomeu said.
Jay Marciano, the president of AEG Europe which owns the O2 Arena, added: "The O2 is no stranger to basketball as it has hosted regular season NBA games and we are proud that Euroleague has chosen it to host the next two Final Four tournaments.
"I am personally looking forward to it after two extremely successful Final Fours at brethren O2 venues in Berlin 2009 and Paris 2010."
Six-times Euroleague winners CSKA Moscow take on 1997 champions Olympiacos in this season's final in Istanbul's Sinan Erdem Arena later on Sunday.
Outgoing holders Panathinaikos meet 2010 champions Barcelona in the day's curtain-raising third place play-off.