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Kante trudged off against Leicester after little more than half an hour, complaining of twinges in his hamstrings.
The World Cup-winning midfielder has been in sparkling form at the end of this campaign and boss Tuchel has admitted Kante's presence can transform the Blues.
"I hope that N'Golo is not injured, he told me that he went out before injury," Thomas Tuchel said on Tuesday evening, following the 2-1 win over Leicester.
"He felt his hamstring and was worried that he would get injured if he continued to play.
Speaking to reporters on Friday ahead of Sunday’s Aston Villa trip, Tuchel said: “With N’Golo Kante it's going to be very close but there are some hopes he joins team training tomorrow.
“If not, he'll join on Monday.”