But Benzema sits out the Wanda Metropolitano clash after he picked up an injury at Celtic in the Champions League.
Lucas Vazquez will also have to wait until after the international break to make his comeback although Real have been boosted by the return of Eder Militao to training.
Antonio Rudiger makes way for the Brazilian if he is confirmed as fit and Ferland Mendy comes in for Nacho at the back.
Late goals from Fede Valverde and Marco Asensio sealed a win over RB Leipzig in midweek and Carlo Ancelotti is set to keep the Uruguayan midfielder in his line-up.
Toni Kroos starts ahead of Aurelien Tchouameni in an otherwise settled XI. Eden Hazard and Asensio are on the bench.
Confirmed team news
— Real Madrid C.F. 🇬🇧🇺🇸 (@realmadriden) September 18, 2022
Real Madrid XI: Courtois, Carvajal, Militao, Alaba, Mendy, Tchouameni, Kroos, Modric, Valverde, Vinicius, Rodrygo
Subs: Lunin, Luis Lopez, Vallejo, Nacho, Hazard, Asensio, Camavinga, Odrioziola, Ceballos, Rudiger, Mariano