While a relatively simple task on paper, the team dubbed the Mountaineers who are ranked 92nd in the world beat Stephen Kenny’s side in the reverse fixture of their Group B1 campaign.
Since then, a big win over Scotland and draw with Ukraine have been the only high points of a disappointing spell for Ireland.
Still, Armenia were smashed 5-0 by Ukraine last week and have conceded 14 goals in their five group games so far.
Here are all the details for tuning in...
Where to watch Republic of Ireland vs Armenia
TV channel: In the UK, Premier Sports 2 will broadcast the game with coverage starting at 7.15pm BST ahead of a 7.45pm kick-off.
Live stream: Those with a Premier Sports subscription can also watch the action unfold online via the Premier Player.