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His absence is the latest blow for Eoin Morgan’s No1-ranked side, who are already without both Jofra Archer and Ben Stokes for the tournament.
The injury must also make Curran a doubt for this winter’s Ashes series, which remains scheduled to begin on December 8, though the ECB are set to make a decision on the viability of the tour this week as concerns persist about quarantine requirements and living arrangements for players and their families in Australia.
An ECB statement said: “Curran complained of back pain after Chennai Super Kings Indian Premier League fixture on Saturday against Rajasthan Royals. Results of the scan revealed the injury.
“He will fly back to the UK in the next couple of days and will have further scans and a full review later this week from the ECB’s medical team.”
England’s non-IPL players arrived in Oman on Tuesday morning, where they will be based until moving to Dubai on October 16 to begin their tournament against the West Indies in a repeat of the 2016 final two days later.