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Saracens 69 Ampthill 12
Saracens' Lions contingent came through unscathed from another outing in the Championship, with all five of Mako Vunipola, Jamie George, Maro Itoje, Owen Farrell and Elliot Daly replaced before the 60-minute mark as Saracens ran in 11 tries against Ampthill.
The visitors, in sixth place ahead of kick-off after three wins from seven games this season, had their moments in attack but couldn't live with Saracens defensively.
Nick Tompkins, Sean Maitland, Ali Crossdale and Tom Woolstencroft all scored braces, with England captain Farrell kicking six conversions before being replaced by Alex Goode on his return for Saracens after playing in Japan. The result means Saracens move up to second and close the gap behind Championship leaders Ealing to five points.
Wales centre Tompkins opened the scoring with a pick-and-go, followed by a straightforward rolling maul try for George off a maul. Tompkins was soon over for his second, assisted by Billy Vunipola after the No 8 broke off a scrum.
Credit to Ampthill for putting Saracens under pressure, winning a succession of penalties and eventually scoring off a maul through hooker Syd Blackmore.
Sarries responded with Sean Maitland crossing in the corner to finish off a slick Saracens attack, with Farrell, George and Daly all involved in the build-up. Farrell, previously perfect with three conversions, missed from the right touchline.
Despite the best efforts of Itoje to slow it down Ampthill's maul was still an effective weapon, dominating possession and territory for a while but failing to convert, with matters made worse by a yellow card for Will Porter for a trip on Maitland.
Saracens made Ampthill pay, feigning to drive with the maul before George and Aled Davies broke down the blindside, making the most of an overlap for Maitland to stroll over for his second, with Farrell's conversion making the score 33-7 at half-time.
Crossdale continued the scoring after half-time, running onto Farrell's cross-field kick, before Mako Vunipola and George were withdrawn two minutes into the second half. Promising full-back Elliott Obatoyinbo then scored Saracens' seventh, stepping his way over after Daly's pass.
Saracens maul was just too strong, Tom Woolstencroft next to score from the set-piece having replaced George in what proved to be Itoje's last action for the evening. Woolstencroft was soon over for a second from the maul.
Ampthill deserved a second try for their efforts and grabbed one through Spencer Sutherland, running onto Louis Grimoldby's grubber, before more fine footwork from Obatoyinbo to set up Crossdale and a long-range break finished by Dom Morris concluded the rout for Saracens.