England will begin the 2023 World Cup against Argentina in Marseille, while Scotland will take on defending champions South Africa in the same city a day later.
Both matches will be played at the Stade Velodrome, on Saturday, September 9 and Sunday, September 10.
Hosts France will face three-time winners New Zealand in a tantalising opening match of the tournament at the Stade de France in Paris on September 8.
After their Pool D opener against Los Pumas, Eddie Jones’ 2019 runners-up will take on Japan in Nice on September 17 before back-to-back games in Lille against qualifiers from the Americas and Oceania on September 23 and October 7 respectively.
Wales, meanwhile, begin their Pool C campaign against Fiji in Bordeaux on September 10 and take on two-time champions Australia in Lyon a fortnight later.
Ireland’s quest to progress beyond the quarter-finals for the first time also starts in Bordeaux, where they will play a European qualifier on September 9.
Andy Farrell’s men face the Springboks in Paris on September 23 and will then return to the Stade de France to complete their Pool B games against rivals Scotland on October 7.
Games will be played at nine venues across France.
The final – scheduled for Saturday, October 28 – the third-placed play-off, both semi-finals and two of the quarter-finals will be staged at the Stade de France.
Marseille will host the other two last-eight fixtures.