It is fair to say neither side has enjoyed a hugely successful campaign, but both Spurs and the Gunners are looking to end it on a high as they chase Champions League qualification.
This Premier League fixture is simply a must-not-lose for both managers, as a defeat would mean a year outside of Europe's top club competition at a time when money is already tight for the north London rivals.
Date, time and venue
Tottenham vs Arsenal is scheduled for a 4:30pm BST kick-off on Sunday, July 12, 2020.
The match will be behind closed doors at the Tottenham Hotspur Stadium with no fans due to be present inside the stadium due to government guidelines regarding coronavirus.
How to watch
TV channel: Tottenham vs Arsenal will be shown live on Sky Sports' Premier League and Main Event channels and is available via Now TV with a day pass for £9.99, or a three-month pass on offer for £25.
Live stream: Sky Sports subscribers can stream the match online via SkyGo and the SkyGo app, with a mobile month pass available for £5.99.
Spurs remain without Eric Dier, who is currently serving a four-match ban for confronting a fan in the Tottenham stands during Spurs' FA Cup exit to Norwich.
Juan Foyth and Japhet Tanganga are out injured, leaving Mourinho with a defensive headache.
As for Arsenal, Calum Chambers, Brend Leno and Gabriel Martinelli (all knee) are out, along with Pablo Mari (ankle).
Mesut Ozil (back) has been missing with an injury and could be an option, though Matteo Guendouzi is out of the picture due to disciplinary issues.
Arsenal are appealing Eddie Nketiah's red card against Leicester, and hope to have the striker available.
Prediction: Tottenham 2-2 Arsenal
Given the importance of this fixture, it should be a cagey affair. Much will depend on whether Arteta can outwit Mourinho, and who can exploit defensive weaknesses more effectively.
Head to head (h2h) history and odds
Of the 55 Premier League north London derbies, Arsenal have won 20 to Spurs' 12, along with 23 draws.
Arsenal are unbeaten in the last three League meetings, with the last result a 2-2 draw at the Emirstes last September.
Regarding all-time results in a fixture which dates back to 1909, Arsenal have collected 82 wins and 53 draws to Spurs' 64 victories.
Spurs to win: 13/8
Arsenal to win: 15/8
Draw: Between 5/2 and 13/5
Over 3.5 goals: 11/5
Odds courtesy of Betfair Exchange. Click here to find out more.
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