Henry Domercant and Vladimir Veremeenko led the way as the Russian side moved level with Montepaschi at the top of Group D.
Domercant drained 24 points while Veremeenko had 21 with 10 rebounds. Lynn Greer added 12 off the bench.
Elsewhere, another Russian team
Nenad Krstic inspired CSKA with 21 points for a victory that takes them to 6-0 for the season. Zalgiris are in real trouble with a 1-5 record.
Vassilis Spanoulis was the hero in Piraeus as his 18 third-quarter points helped lift
Spanoulis finished with a career-high 29 points, helping to seal victory with four clutch free-throws in the final minute.
Rounding off the night's action,