Who will win Real Madrid vs. RB Leipzig? Predictions and odds for Champions League match

UEFA Champions League action has returned this week for the second leg of its round of 16.

La Liga club Real Madrid host Bundesliga's RB Leipzig after taking a 1-0 aggregate lead as the away side in the first leg, nearly one month ago. With Madrid star midfielder Jude Bellingham out with an injury, 24-year-old Brahim Díaz was the hero, scoring the only goal of the game in the 48th minute.

Leipzig will have to outscore Madrid by two goals in Wednesday's second leg at the Santiago Bernabeu to advance to the Champions League quarterfinals.

Here's everything to know about Wednesday's Champions League matchup.

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Real Madrid vs. RB Leipzig predictions

Sportskeeda: Real Madrid 2, RB Leipzig 0

Aditya Hosangadi writes, "Real Madrid are the better team at the moment and should be able to win this game."

Pickswise: Real Madrid to win

Joe Casey writes, "With Carlo Ancelotti’s men winning 15 of their 18 home games in all competitions – losing none – it is hard to look past a victory for Real Madrid."

Action Network: Take the under on goals scored

Anthony Dabbundo writes, "Real Madrid rarely looked troubled in the final 30 minutes once defending a 1-0 lead out of possession. The Bundesliga's contenders have all taken a real step back this season in overall quality — mainly Dortmund, Leipzig and the Europa League teams — and Leipzig may find themselves with a lot of stale possession that leads to few shots in this matchup."

Sports Illustrated: Real Madrid to win, 2-0

Dylan Clemons writes, "[H]eading on the road and missing strong defender Mohamed Simakan definitely hurts [Leipzig's] chances..."

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Real Madrid vs. RB Leipzig: Odds and lines for Champions League match

Real Madrid are favorites to defeat RB Leipzig in Wednesday's Champions League match according to the BetMGM soccer odds. Looking to wager? Check out the best mobile sports betting apps offering sports betting promos in 2024.

Odds listed are as of Wednesday morning.

• Lines: Real Madrid (-190); Draw (+350); RB Leipzig (+450)

• Over 3.5 goals (+115)

• Under 3.5 goals (-160)

How to watch Real Madrid vs. RB Leipzig: TV channel and streaming

When: Wednesday, March 6 at 3 p.m. ET/Noon PT

Where: Santiago Bernabéu Stadium, Madrid, Spain

Cable TV: TUDN; Univision

Streaming: Paramount+; fuboTV

How to watch: See all Champions League action with a Fubo subscription

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This article originally appeared on USA TODAY: Real Madrid vs. RB Leipzig: Predictions, odds in Champions League game