Kosgei, who won the Tokyo Marathon earlier this year and claimed a silver medal at last year’s Olympics, was among the favourites heading into the weekend event, as she aimed to add to his 2019 and 2020 triumphs in the capital.
A statement read: “I have been struggling over the past month with an issue in the hamstring of my right leg. My training has been up and down and not the way I would like to prepare to be in top condition for the 2022 TCS London Marathon.”
"We've decided it's best I withdraw from this year's race and get further treatment on my injuries in order to enter 2023 stronger than ever."
Kosgei set a world record time of 2:14:04 in Chicago in 2019. She was upset in London last year when she finished fourth in a race won by her compatriot Joyciline Jepkosgei, who is set to headline the event this weekend.
Additional reporting by Reuters.