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NFL inactives Week 10: 49ers RB Christian McCaffrey active for first time in 2024 season

Here's everything you need to know injury-wise for Week 10

sean leahy · liz roscher
·4-min read

Christian McCaffrey is active for the San Francisco 49ers for the first time this season. After what head coach Kyle Shanahan called an "awesome" performance at practice the past two days, McCaffrey will make his season debut against the Tampa Bay Buccaneers on Sunday. He was officially activated off injured reserve on Saturday.

McCaffrey has been out all season due to Achilles tendinitis and calf tightness, with trouble first coming when he was a late scratch in Week 1. He was soon placed on injured reserve, with a hazy timetable to return to the field.

He underwent treatment from a specialist in Germany in September and didn't return to practice until this week. This week, he has been listed as a limited participant in practice.

With McCaffrey out, the 4-4 Niners have struggled to replicate their success from last season, due to both the running back's absence and other factors. Jordan Mason has handled the bulk of running duties, posting 685 rushing yards and three touchdowns while averaging 5.1 yards per carry (McCaffrey averaged 5.4 yards last season).

Here are the inactives for Week 10. (Players will be added as teams release their reports.)

  • G Tyrese Robinson

  • DE Yannick Ngakoue

  • WR Tyquan Thornton

  • S Kyle Dugger

  • LB Christian Elliss

  • DT Eric Johnson

  • QB Joe Milton III

  • DB Jaquan Brisker

  • LB Noah Sewell

  • OL Darnell Wright

  • OL Braxton Jones

  • DB Ameer Speed

  • DL Darrell Taylor

  • OL Nate Davis

  • OL Kiran Amegadjie

  • WR Keon Coleman

  • WR Amari Cooper

  • FB Reggie Gilliam

  • LB Edefuan Ulofoshio

  • OL Will Clapp

  • WR KJ Hamler

  • QB Sam Ehlinger

  • WR Anthony Gould

  • WR Michael Pittman Jr.

  • S Darren Hall

  • DE Genard Avery

  • DT Adam Gotsis

  • QB Zach Wilson

  • CB Kris Abrams-Draine

  • DB Keidron Smith

  • T Frank Crum

  • G Calvin Throckmorton

  • TE Greg Dulcich

  • DL Eyioma Uwazurike

  • WR JuJu Smith-Schuster

  • RB Clyde Edwards-Helaire

  • OL C.J. Hanson

  • T Ethan Driskell

  • DT Marlon Tuipulotu

  • DE Cameron Thomas

  • RB Jase McClellan

  • ILB JD Bertrand

  • ILB Rashaan Evans

  • DL Brandon Dorlus

  • OL Jovaughn Gwyn

  • OL Elijah Wilkinson

  • T Brandon Parker

  • WR Cedrick Wilson

  • CB Kool-Aid McKinstry

  • QB Spencer Rattler

  • RB Jamaal Williams

  • LB Jaylan Ford

  • G/C Lucas Patrick

  • DT Khristian Boyd

  • QB Joshua Dobbs

  • WR Chris Conley

  • DL Kevin Givens

  • OL Ben Bartch

  • CB Charvarius Ward

  • TE Brayden Willis

  • DL Earnest Brown

  • TE Devin Culp

  • WR Mike Evans

  • LB Antonio Grier

  • G Royce Newman

  • OLB Jose Ramirez

  • S Tykee Smith

  • QB Kyle Allen

  • WR Scott Miller

  • CB C.J. Henderson

  • LB Nick Herbig

  • OG Max Scharping

  • K Austin Seibert

  • RB Brian Robinson Jr.

  • QB Jeff Driskel (3rd QB)

  • S Darrick Forrest

  • CB Marshon Lattimore

  • LB Dominique Hampton

  • T Cornelius Lucas

  • QB Brett Rypien

  • CB Fabian Moreau

  • CB Dwight McGlothern

  • DL Levi Drake Rodriguez

  • OL Dan Feeney

  • T Walter Rouse

  • QB Trevor Lawrence

  • DE Myles Cole

  • OL Ezra Cleveland

  • DT Esezi Otomewo

  • DT Maason Smith

  • CB L'Jarius Sneed (quad): out

  • RB Julius Chestnut (foot): questionable

  • T Dillon Radunz (toe): questionable

  • CB Kristian Fulton (hamstring): doubtful

  • OLB Joey Bosa (hip): questionable

  • RB Gus Edwards (ankle): questionable

  • OLB Khalil Mack (groin): questionable

  • LB Denzel Perryman (toe): questionable

  • T Trey Pipkins (ankle): questionable

  • TE Stone Smartt (ankle): questionable

  • LB Ben VanSumeren (concussion): questionable

  • QB Dak Prescott (hamstring): out

  • CB DaRon Bland (foot): out

  • S Juanyeh Thomas (concussion): out

  • CB Trevon Diggs (calf, illness): questionable

  • T Tyler Guyton (neck, shoulder): questionable

  • LB Eric Kendricks (shoulder): questionable

  • DE Micah Parsons (ankle): questionable

  • LB Nick Vigil (foot): questionable

  • RG Jake Hanson (hamstring): out

  • LB C.J. Mosley (neck): out

  • CB Michael Carter II (back): questionable

  • OL Morgan Moses (knee): questionable

  • DL Solomon Thomas (knee): questionable

  • G Alijah Vera-Tucker (ankle/non-injury/personal): questionable

  • LB Chazz Surratt (heel): questionable

  • TE Tyler Conklin (ankle): questionable

  • DT Darius Robinson (calf): out

  • S Jalen Thompson (ankle): questionable

  • T Jonah Williams (knee): questionable

  • T Taylor Decker (shoulder): out

  • DT Brodric Martin (knee): out

  • LB Jalen Reeves-Maybin (neck): out

  • S Ifeatu Melifonwu (ankle): out

  • CB Emmanuel Moseley (pectoral): out

  • LB Malcolm Rodriguez (ankle): out

  • DE Za'Darius Smith (personal): questionable

  • DE Will Anderson Jr. (ankle): out

  • RB Dameon Pierce (groin): out

  • DT Foley Fatukasi (groin, shoulder): questionable

  • LB Jake Hansen (ankle): questionable

  • DE Jerry Hughes (hip): questionable

  • CB Jeff Okudah (quad): questionable

  • WR Tank Dell (back): questionable

  • WR Nico Collins (hamstring): questionable

  • OL Austin Jackson (knee): out

  • S Jevon Holland (hand/knee): questionable

  • FB Alec Ingold (calf): questionable

  • S Patrick McMorris (calf): questionable

  • WR River Cracraft (shoulder): questionable

  • WR Tyreek Hill (wrist): questionable

  • OT Rob Havenstein (ankle): out

  • DT Neville Gallimore (shoulder): out

  • S Kam Curl (knee): questionable

  • G Kevin Dotson (ankle/knee): questionable

  • LB Christian Rozeboom (neck): questionable

  • WR Darius Slayton

  • S Jason Pinnock

  • WR Bryce Ford-Wheaton

  • LB Darius Muasau

  • DL Jordon Riley

  • OL Jake Kubas

  • QB Tommy DeVito

  • S Jammie Robinson

  • RB Jonathon Brooks

  • CB Shemar Bartholomew

  • OLB Charles Harris

  • LT Ikem Ekwonu

  • TE Tommy Tremble

  • DT Jaden Crumedy