Irvin drove Carr into the ground on the tackle and incurred a roughing-the-passer penalty for the play.
Carr was evaluated by two trainers before leaving the field with more than 10 minutes left as the Saints trailed 33-21.
He was listed as doubtful to return with shoulder and back injuries while also having to go through the concussion protocol. Carr finished with 226 yards, one touchdown and one interception on 17-of-22 passing.
Carr signed a four-year, $150 million contract with the Saints in March with $60 million guaranteed at signing and $100 million guaranteed.
This article originally appeared on USA TODAY: Derek Carr injury: Saints QB leaves game after taking big hit